Sanctum

37 Games with a sci-fi setting like Sanctum that you should try

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We filtered the 50 games similar to Sanctum down to the 37 that fit the “Sci-Fi” category. Borderlands 4, Ratchet: Deadlocked and Iron Grip: Warlord top the list, ranked by affinity and similarity score to Sanctum.

iRank72/ 100

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GenreShooterSubgenreFPS

Tags

CasualSoloMultiplayer

Year 2011Dev Coffee Stain Studios

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Quick answer

Within the “Sci-Fi” category, the closest game to Sanctum is Borderlands 4 — scoring 95/100 on our similarity scale. Ratchet: Deadlocked and Iron Grip: Warlord follow close behind.

#1Borderlands 495 #2Ratchet: Deadlocked95 #3Iron Grip: Warlord94 #4Syndicate93 #5Overwatch93

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The best games with a sci-fi setting like Sanctum

37 similar games foundUpdated July 2026

Handpicked by our similarity algorithm, these are the titles with the highest gameplay match to Sanctum. Each one has been evaluated across 12 real attributes — from combat style and progression mechanics to world structure and visual perspective — so every recommendation is based on how the game actually plays, not just its genre label.

#1Borderlands 4

95

Borderlands 4

GenreShooterSubgenreFPS

SoloMultiplayerCo-opSci-FiFirst Person

Steam👍 59%· 79KIGDB87· 4OC82· 140

Year 2025Dev Gearbox Software · 2KOn Xbox · Switch · PC

✓ Same family of first-person shooters: shooter, first-person shooting and setting scifi

≠ Its own twist: deep RPG systems and adventure storytelling, while skipping tower defense planning

Steam Epic Xbox

#2Ratchet: Deadlocked

95

Ratchet: Deadlocked

GenreShooterSubgenreFPS

SoloMultiplayerCo-opSci-FiFirst Person

IGDB70· 1

Year 2005Dev Insomniac Games · Sony Computer Entertainment

✓ Fits the first-person shooters cluster, with shooter, first-person shooting and setting scifi

≠ Where it differs: brings precision platforming, adventure storytelling and exploration and discovery, while skipping tower defense planning

#3Iron Grip: Warlord

94

Iron Grip: Warlord

GenreShooterSubgenreFPS

Co-opSoloMultiplayerMeleeRangedSci-FiFirst Person

Steam👍 85%· 448MC59

Year 2008Dev ISOTXPlaytime ~1hOn PC

✓ Fits the first-person shooters cluster, with shooter, first-person shooting and tower defense planning

≠ Where it differs: brings real-time strategy, fantasy world and visual isometric, while skipping vibe casual

93

Syndicate

GenreShooterSubgenreFPS

SoloMultiplayerCo-opSci-FiFirst Person

IGDB79· 6

Year 2012Dev Starbreeze Studios · Electronic ArtsOn PlayStation 3 · PC

✓ Both are first-person shooters — sharing shooter, first-person shooting and setting scifi

≠ Its own twist: puzzle design and setting cyberpunk, while skipping tower defense planning

93

Overwatch

GenreShooterSubgenreFPS

SoloMultiplayerCo-opSci-FiFirst Person

Steam👍 30%· 401KIGDB83· 3OC90· 138

Year 2023Dev Blizzard EntertainmentOn Xbox · PS4 · Switch

✓ Fits the first-person shooters cluster, with shooter, first-person shooting and setting scifi

≠ Its own twist: PvP competition, visual third person and free to play, while skipping tower defense planning

Steam Xbox Nintendo

#6Lost Planet 2

92

Lost Planet 2

GenreShooterSubgenreFPS

Co-opSoloMultiplayerOnlineMeleeSci-Fi

Steam👍 66%· 3.0KIGDB71· 6

Year 2010Dev CapcomOn PlayStation 3 · Linux · PC

✓ Same family of first-person shooters: shooter, first-person shooting and melee combat

≠ Where it differs: brings adventure storytelling, third-person shooting and skill tree progression, while skipping tower defense planning

92

Broforce

GenreShooterSubgenreFPS

MultiplayerCo-opSoloMeleeRangedCasualSci-Fi

Steam👍 97%· 61KRAWG👍 84%· 1.3KMC83IGDB72· 9OC79· 43

Year 2015Dev Devolver DigitalPlaytime ~6hOn PC · PS · Apple Macintosh

✓ Both are first-person shooters — sharing shooter, first-person shooting and vibe casual

≠ Where it differs: brings adventure storytelling, precision platforming and dark, oppressive atmosphere, while skipping tower defense planning

#8Zombie Panic! Source

91

Zombie Panic! Source

GenreShooterSubgenreFPS

MultiplayerCo-opOnlineMeleeRangedCasualSci-FiFirst Person

Steam👍 85%· 7.8KRAWG👍 56%· 24

Year 2008Dev Zombie Panic TeamPlaytime ~1hOn PC

✓ Same family of first-person shooters: shooter, first-person shooting and vibe casual

≠ Its own twist: adventure storytelling, survival mechanics and horror tension, while skipping tower defense planning

#9Star Fox Zero

91

GenreShooterSubgenreFPS

SoloCo-opSci-FiFirst PersonThird Person

IGDB67· 13OC69· 86

Year 2016Dev PlatinumGames · Nintendo of Europe

✓ Both are first-person shooters — sharing shooter, first-person shooting and setting scifi

≠ Its own twist: adventure storytelling and visual third person, while skipping tower defense planning

91

Prey

GenreShooterSubgenreFPS

SoloMultiplayerMeleeRangedSci-FiFirst Person

IGDB77· 4OC81· 166

Year 2006Dev Human Head Studios · SkyZone EntertainmentOn Linux · PC · Mac

✓ Same family of first-person shooters: shooter, first-person shooting and melee combat

≠ Its own twist: puzzle design, while skipping tower defense planning

#11Transformers: Fall of Cybertron

90

Transformers: Fall of Cybertron

GenreShooterSubgenreFPS

SoloMultiplayerCo-opMeleeSci-Fi

Steam👍 93%· 2.5KIGDB81· 11

Year 2012Dev High Moon Studios · ActivisionOn PlayStation 3 · PS4 · PC

✓ Same family of first-person shooters: shooter, first-person shooting and melee combat

≠ Its own twist: third-person shooting, adventure storytelling and visual third person, while skipping tower defense planning

#12Metroid Prime Hunters

90

Metroid Prime Hunters

GenreShooterSubgenreFPS

SoloMultiplayerSci-FiFirst PersonExploration

IGDB87· 3

Year 2006Dev Nintendo Software Technology · Nintendo

✓ Both are first-person shooters — sharing shooter, first-person shooting and setting scifi

≠ Its own twist: precision platforming, adventure storytelling and Metroidvania exploration, while skipping tower defense planning

#13Metroid Prime 2: Echoes

90

Metroid Prime 2: Echoes

GenreShooterSubgenreFPS

SoloMultiplayerSci-FiFirst PersonExploration

IGDB80· 2

Year 2004Dev Retro Studios · Nintendo

✓ Fits the first-person shooters cluster, with shooter, first-person shooting and setting scifi

≠ Stands apart with precision platforming, adventure storytelling and Metroidvania exploration, while skipping tower defense planning

90

Unreal

GenreShooterSubgenreFPS

SoloMultiplayerSci-FiFirst Person

Year 1998Dev Digital Extremes · GT Interactive SoftwareOn PC · Mac

✓ Fits the first-person shooters cluster, with shooter, first-person shooting and setting scifi

≠ Stands apart with precision platforming, while skipping tower defense planning

#15Ratchet & Clank: Size Matters

90

Ratchet & Clank: Size Matters

GenreShooterSubgenreFPS

SoloMultiplayerSci-FiFirst PersonExploration

IGDB60· 6

Year 2007Dev High Impact Games · Sony Computer Entertainment

✓ Fits the first-person shooters cluster, with shooter, first-person shooting and setting scifi

≠ Stands apart with precision platforming, adventure storytelling and exploration and discovery, while skipping tower defense planning

Complete list of games with a sci-fi setting like Sanctum

The full catalog of games sharing gameplay DNA with Sanctum, ordered from highest to lowest similarity score. Use the filters above to narrow down by genre, setting or game mode and find the alternative that best fits your playstyle.

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